structure attaching chromosomes to microtubules of mitotic spindle. Microtubule-organizing center located on chromosomes. Centromeric connections to the spindle are required for chromatid segregation. The centromere, as a region of the chromosome deduced from genetic behavior, is sometimes distinguished from kinetochore (a structure observable in the electron microscope). Some authors consider centromere synonymous with kinetochore. In some parabasalians, centromeres are embedded in the nuclear membrane.

Alternative form for centromere : centromeres.